Computational Challenges and Opportunities in Personalized Medicine

Rapid progress in systems biology and molecular analytical platforms offers the promise of major gains in the detection, treatment and prevention of diseases and for targeting therapeutic interventions to match the molecular and pharmacogenetic profiles of individual patients (personalized medicine). Whole genome sequencing and other molecular diagnostics, next-generation body imaging and miniaturized on-body:in-body sensors will assume increasing importance in the healthcare value chain as powerful platforms for precision diagnosis, selection of optimum treatment, treatment compliance and remote monitoring of individual health status.